Museum London is a multidisciplinary institution, housing and exhibiting works of historical art, contemporary art and historical artifacts. The term 'museum' provides a comprehensive description of what we do and references the artifacts we exhibit as well as both historical and contemporary art (i.e. Museum of Modern Art, New York). The term would refer only to art, disregarding the important historical aspect to our organization.

Museum London was established in 1940 and operated from the London Public Library until 1980 when the renowned Canadian architect Raymond Moriyama was commissioned to design its current home at the forks of the Thames River in downtown London, Ontario. In 1989, the then London Regional Art Gallery amalgamated with the London Historical Museum creating what is known today as Museum London.

In the spirit of Truth and Reconciliation we would like to acknowledge that Museum London operates within the traditional territory of the Anishinaabeg, Haudenosaunee, Attawandaron (Neutral), and Wendat peoples. This territory is covered by the Upper Canada Treaties. This territory is the homeland of the Chippewas of the Thames First Nation, Oneida Nation of the Thames, and Munsee Delaware Nation. We also recognize the contributions of Métis, Inuit, and other Indigenous peoples, both in shaping and strengthening this community in particular, and our province and country as a whole.

Museum London's activities are driven by a mandate to collect, preserve, exhibit and interpret the visual arts and local history. We present a dynamic mix of interconnected exhibitions and programs that have both local and national relevance. Our exhibitions and programs are often cross-disciplinary, augmented by interpretative material, publications, symposia, discussions, lectures, films or other events. As such, they provide visitors with a range of interactive, interpretive experiences.

Museum London is governed by a Board of Directors comprised of 15 members elected from the general membership, artists and appointments from various stakeholder groups including the City of London, the London and Middlesex Historical Society and the Canadian Artists' Representation organization.

The Museum employs 18 full-time and 15 part-time staff members, and a group of 185 docents and volunteers who provide tours, staff the Museum shop, Muse Shop + Rental and develop numerous fundraising initiatives.